THE LENGTH OF VESICULAR STOMATITIS VIRUS PARTICLES DICTATES A NEED FOR ACTIN ASSEMBLY DURING CLATHRIN-DEPENDENT ENDOCYTOSIS.

The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin-dependent endocytosis.

Microbial pathogens exploit the clathrin endocytic machinery to enter host cells.Vesicular stomatitis virus (VSV), an enveloped virus with bullet-shaped virions that measure 70 x 200 nm, enters cells by clathrin-dependent endocytosis.We showed previously that VSV particles exceed the capacity of typical clathrin-coated vesicles and instead enter th

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Management of acute aortic syndrome with evolving individualized precision medicine solutions: Lessons learned over two decades and literature review

BackgroundThoracoabdominal acute aortic syndrome is associated with high morbidity and mortality.We aim to scrutinize our evolving strategies for acute aortic syndrome (AAS) management using minimally invasive and adaptive surgical techniques over two decades.MethodsThis is a longitudinal observational study at our tertiary vascular centre from 200

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